Obezita jako příčina nedostatku vitamínu D

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Obezita jako příčina nedostatku vitamínu D

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Nové studie potvrzují to, co očekávali již nějakou dobu zdravotníci. Studie publikovaná v časopise PLoS Medicine poskytuje významné důkazy, že je obezita skutečnou příčinou nedostatku vitamínu D.

Už některé předchozí studie ukázaly silnou korelaci mezi obezitou a nízkou hladinou vitamínu D. Nicméně nová studie je první, která prokázala příčinnou souvislost, tedy že obezita je důvodem nedostatku vitamínu D než aby tomu bylo naopak.

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ZOBRAZIT

Výzkumníci zkoumali 21 samostatných studií na celkem 42 024 dospělých evropského původu, aby získali nezbytná data. A to nejen o vitamínu D, ale i indexu tělesné hmotnosti BMI a 12ti samostatných genetických variací pro predispozici k obezitě.

Vědci předpokládali, že je-li obezita příčinou nedostatku vitamínu D, pak by u lidí s vysokou genetickou predispozicí k obezitě měly být nižší hladiny vitamínu D. Naproti tomu, měl-li by být nedostatek vitamínu D důvodem obezity, pak by genetická predispozice k nedostatku vitamínu měla být spojena s vyšší obezitou.

Po prostudování závěrů předchozích studií vědci zjistili, že každé 1 kg/m2 zvýšení BMI bylo spojeno s 1,15 % nižší koncentrací vitamínu D v krvi. V samotné statistické analýze vědci také zjistili, že 10% zvýšení BMI vedlo k 4,2% snížení hladiny vitamínu D. Všechna data podléhala přísné kontrole vlivu potenciálních matoucích faktorů.

Vědci dále zjistili, že lidé s vyšší genetickou predispozicí k obezitě měli oba vyšší BMI a nižší hladinu vitamínu D. Ale zatímco lidé, kteří byli geneticky náchylní k nedostatku vitamínu D skutečně mají nižší hladinu vitamínu D, přičemž neměli vyšší BMI než u predisponovaných jedinců.

Tudíž je zřejmé, že obezita je příčinou nedostatku vitamínu D nikoliv naopak. Mnozí vědci se domnívají, že protože je vitamín D rozpustný v tucích, může být v těle obézních "uvězněn" v nadměrných tukových zásobách bez schopnosti vstoupit do krevního řečiště.

To neznamená, že jsou obézní jedinci odsouzení k nedostatku vitamínu D. Stejně jako všichni lidé, i obézní jedinci mohou výrazně zvýšit hladinu vitamínu D zvýšením přísunu v potravě a vystavováním slunečnímu záření bez opalovacího krému.

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Zdroj
Autor/zdroj fotografie: Pavel Hanzal

Štítky: jídlo, vitamín D

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